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GenScript corporation
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AECOM International Development
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Image Search Results
Journal: Oncotarget
Article Title: Gene master regulators of papillary and anaplastic thyroid cancers
doi: 10.18632/oncotarget.23417
Figure Lengend Snippet: (A) Examples of genes (including known TC biomarkers) with large GCH differences in the two cell lines. (B) Average expression level (AVE), coefficient of variation (CV) and GCH of the selected genes in the two cell lines before any transfection. X = expression ratio, CUT = absolute fold-change cut-off for significantly differentially expressed genes, P-VAL = p-value of the differential expression. (C) Characteristics of the transfected clones. In all transfections, we used the same lentiviral vector pLX304. (D-G) GCH vs % regulated genes for each transfection experiment. Note that always, higher GCH is associated with larger percentage of regulated genes. (H) GCH increases with GCH in each cell type. Strong positive Pearson product-momentum correlations (r = 0.914 for BCPAP and r = 0.873 for 8505C cells) were found between the GCH scores and the percentage of significantly regulated genes in both cell lines.
Article Snippet: The stable transfection was performed using plasmids in
Techniques: Expressing, Transfection, Clone Assay, Plasmid Preparation